Transplacental infection of a foal with Anaplasma phagocytophilum
نویسندگان
چکیده
منابع مشابه
Mechanisms of obligatory intracellular infection with Anaplasma phagocytophilum.
Anaplasma phagocytophilum persists in nature by cycling between mammals and ticks. Human infection by the bite of an infected tick leads to a potentially fatal emerging disease called human granulocytic anaplasmosis. A. phagocytophilum is an obligatory intracellular bacterium that replicates inside mammalian granulocytes and the salivary gland and midgut cells of ticks. A. phagocytophilum evolv...
متن کاملCavitary Effusion Associated with Anaplasma phagocytophilum Infection in 2 Equids
A 15-year-old, 558-kg Quarter Horse gelding was examined because of peripheral edema and bicavitary (pleural and abdominal) effusion, identified via field ultrasonography before referral. Two years earlier, the horse was evaluated for a similar clinical presentation, including peripheral edema, bicavitary effusion, and fever. The gelding was diagnosed with Anaplasma phagocytophilum infection by...
متن کاملStat1 negatively regulates immune-mediated injury with Anaplasma phagocytophilum infection.
Human granulocytic anaplasmosis (HGA) is caused by the obligate intracellular bacterium Anaplasma phagocytophilum. Our data previously demonstrated that A. phagocytophilum induces an immunopathologic response by activating IFN-γ production through the Stat1 signaling pathway. In this study, we investigated the broader role of Stat1 signaling in the host response to infection with A. phagocytoph...
متن کاملTick-Borne Fever (Anaplasma phagocytophilum Infection) in Sheep – A Review
Ticks may transmit pathogens to ruminants worldwide, creating diseases such as anaplasmosis, babesiosis, ehrlichiosis and theileriosis. In Europe, the most important tick vector is Ixodes ricinus and the most widespread tick-borne infection in animals is Anaplasma phagocytophilum. This infection causes tick-borne fever (TBF) in ruminants, a disease which may not only cause suboptimal growth, bu...
متن کاملTransformation of Anaplasma phagocytophilum
BACKGROUND Tick-borne pathogens cause emerging zoonoses, and include fastidious organisms such as Anaplasma phagocytophilum. Because of their obligate intracellular nature, methods for mutagenesis and transformation have not been available. RESULTS To facilitate genetic manipulation, we transformed A. phagocytophilum (Ap) to express a green fluorescent protein (GFP) with the Himar1 transposas...
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ژورنال
عنوان ژورنال: Equine Veterinary Education
سال: 2019
ISSN: 0957-7734,2042-3292
DOI: 10.1111/eve.13233